本文采用的英格恩产品: CCAA细胞凋亡检测试剂盒(PI)
Patient, family and clinician priorities for critical care research in Asia and Africa: a James Lind Alliance Priority Setting Partnership using modified Delphi and nominal group techniques
Affiliations
- 1 The Aga Khan University Hospital Nairobi, Nairobi, Nairobi County, Kenya.
- 2 Amsterdam Public Health, Amsterdam University Medical Centre (UMC),Amsterdam Medical Centre (AMC), Amsterdam, The Netherlands.
- 3 Research and Development, The George Institute for Global Health India, New Delhi, India.
- 4 Nepal Intensive Care Research Foundation (NICRF), Kathmandu, Central Development Region, Nepal.
- 5 D’Or Institute for Research and Education, Rio de Janeiro, RJ, Brazil.
- 6 Pandemic Sciences Hub and Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, Scotland, UK abi@nicslk.com.
- 7 Critical Care, Mahidol Oxford Tropical Medicine Research Unit (MORU), Bangkok, Bangkok, Thailand.
- 8 Doctors with Africa CUAMM (Collegio Universitario Aspiranti e Medici Missionari), Iringa, United Republic of Tanzania.
- 9 Mahidol Oxford Tropical Medicine Research Unit (MORU), Bangkok, Bangkok, Thailand.
- 10 Athena Institute, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
- 11 Hospital Operations, Nepal cancer hospital, Kathmandu, Nepal.
- 12 Department of Applied Health Sciences, University of Birmingham, Birmingham, UK.
- 13 National Institute for Health Research, James Lind Alliance, Southampton, England, UK.
- 14 Pandemic Sciences Hub and Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, Scotland, UK.
- 15 Ziauddin University, Karachi, Sindh, Pakistan.
- 16 Patient and Public Representative, on behalf of CCCG, Apollo Hospitals Group, Chennai, India.
- 17 National Intensive Care Surveillance – MORU (NICS-MORU), Network for Improving Critical Systems and Training, Colombo, Sri Lanka.
- 18 Lung Health Research Group, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Southern Region, Malawi.
- 19 Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, England, UK.
- 20 Department of Nursing, Critical Care, Mulago National Referral Hospital (MNRH), Kampala, Central Region, Uganda.
- 21 Anaesthesiology and Critical Care, International Islamic University Malaysia – Kuantan Campus, Kuantan, Pahang, Malaysia.
- 22 Department of Anesthesiology & Critical Care, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, OD, India.
- 23 Critical Care Research Group, Ziauddin University, Karachi, Sindh, Pakistan.
- 24 Department of Precision-Regenerative Medicine and Jonic Area (DiMePRe-J), Section of Anesthesiology and Intensive Care Medicine, University of Bari Aldo Moro, Bari, Apulia, Italy.
- 25 Anaesthesia & Critical Care, Makerere University, Kampala, Central Region, Uganda.
- 26 Critical care, Instituto D’Or de Pesquisa e Ensino, Rio de Janeiro, RJ, Brazil.
- 27 Research Coordinator, Nepal Intensive Care Research Foundation, Kathmandu, Central Development Region, Nepal.
- 28 Critical Care, Apollo Hospitals, Chennai, India.
- 29 Centre for Inflammation Research, The University of Edinburgh, Edinburgh, Scotland, UK.
- PMID: 41735006
- PMCID: PMC12933803
- DOI: 10.1136/bmjgh-2025-019904
Abstract
Background: This James Lind Alliance (JLA) Priority Setting Partnership aimed to identify and prioritise unanswered questions important to adult patients, their families and health professionals with lived experience of critical care across Asia and Africa.
Methods: Modified Delphi techniques were used to generate suggestions using an online survey. Following verification, literature review and content analysis, these suggestions were iteratively codified into emergent topics. Topics were presented in a second online survey for ranking, prior to an online workshop where nominal group technique was used to identify top priority questions across stakeholder groups. Surveys were disseminated using snowballing techniques.
Findings: The project was coordinated by a representative steering group independently overseen by the JLA. The initial survey generated 432 candidacy suggestions from 17 countries. Review, content analysis and codification resulted in 51 candidacy questions, spanning 16 topics. A second shortlisting survey reached 124 clinicians and 86 patient-carer stakeholders, who ranked the most important topics and produced a shortlist of 18 candidacy topic questions. Representative stakeholders attending an online workshop prioritised the questions, with a tie for 10th and 11th place, resulting in a top 10+1 priority list. These spanned four themes: cost of care, infection and long-term recovery including psychological and socio-economic recovery following critical illness.
Interpretation: Cost, who would benefit from intensive care unit admission and organisation of healthcare dominated discussions irrespective of disease, injury or illness. Priorities were consistent between stakeholder groups. The JLA methodology enabled contributions from those with lived experience of critical care. The results of the prioritisation partnership provide a roadmap for researchers and funders seeking to address stakeholder priorities.
Keywords: Global Health; Health economics; Health services research; Interdisciplinary Research; Public Health.
