Vet Sci. 2026 May 6;13(5):455.doi: 10.3390/vetsci13050455. Efficient and Safe Knockout of AR and DMRT1 Mediated by Cytosine Base Editors in Chicken DF-1 and PGCs胞嘧啶碱基编辑器在鸡DF-1和原始生殖细胞中高效且安全地敲除AR和DMRT1
Fish Shellfish Immunol. 2026 May 4:111388.doi: 10.1016/j.fsi.2026.111388. The function of stearoyl-CoA desaturase in unsaturated fatty acid biosynthesis and cold tolerance in Haliotis discus hannai 硬脂酰辅酶A脱饱和酶在皱纹盘鲍不饱和脂肪酸生物合成及耐寒性中的作用
Biosci Biotechnol Biochem. 2026 Apr 21:zbag054.doi: 10.1093/bbb/zbag054. Effect of pirfenidone on the regulation of lymph angiogenesis by PLK1 signaling to inhibit metastasis of lung cancer in vivo 吡非尼酮通过PLK1信号调节淋巴血管生成以抑制肺癌体内转移的作用
Nat Commun. 2026 Apr 20.doi: 10.1038/s41467-026-72181-6. Photoactivatable CRISPR/Cas13d via upconversion nanoparticles for deep tissue RNA engineering and orthopedic therapy 通过上转换纳米颗粒实现光激活CRISPR/Cas13d，用于深层组织RNA工程和骨科治疗(IF:15.7).
J Mol Endocrinol. 2026 Apr 22:JME-25-0220.doi: 10.1530/JME-25-0220. The Molecular Mechanism of Melatonin in Regulating Osteoporosis Based on the RANKL/OPG Signaling Axis 基于RANKL/OPG信号轴的褪黑素调节骨质疏松症的分子机制
Transl Psychiatry. 2026 Apr 4.doi: 10.1038/s41398-026-04014-5. ECM remodeling in the mPFC exacerbates cocaine-induced hyperactivity and impairs threat vigilance 内侧前额叶皮层（mPFC）中的内皮素转化酶（ECM）重塑会加剧可卡因诱导的多动行为，并损害对威胁的警觉性 (IF:6.2).
Cell Calcium. 2026 Apr 19:135:103137.doi: 10.1016/j.ceca.2026.103137. TRPC1 channel modulates mechanical stretch-induced bone marrow mesenchymal stem cell proliferation through Ca2+-dependent ERK1/2 activation TRPC1通道通过Ca2+依赖的ERK1/2激活调节机械拉伸诱导的骨髓间充质干细胞增殖
Biochem Pharmacol. 2026 Apr:246:117723.doi: 10.1016/j.bcp.2026.117723. Epub 2026 Jan 20. Small nucleolar RNA host gene 3 regulates sepsis-induced acute lung injury and inflammation by targeting microRNA-186-5p (IF:5.6).小核仁RNA宿主基因3通过靶向microRNA-186-5p来调节败血症诱导的急性肺损伤和炎症
Sci Rep. 2026 Apr 9.doi: 10.1038/s41598-026-46857-4. CD204 regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following intracerebral hemorrhage CD204调节小胶质细胞/巨噬细胞M1/M2极化，并缓解脑出血后的神经炎症
Int J Radiat Oncol Biol Phys. 2026 Apr 5:S0360-3016(26)00521-3.doi: 10.1016/j.ijrobp.2026.03.037. Alternative End Joining Dependency Imposed by miR-21-5p Defines Radiation Resistance and a Targetable Vulnerability in Oral Squamous Cell Carcinoma miR-21-5p强加的替代末端连接依赖性定义了口腔鳞状细胞癌的辐射抗性和可靶向的脆弱性 (IF:6.5).
