Int Immunopharmacol. 2024 Oct 25:140:112729.doi: 10.1016/j.intimp.2024.112729. Epub 2024 Aug 3. ADORA3 activation promotes goblet cell differentiation via enhancing HMGCS2-mediated ketogenesis in ulcerative colitis ADORA3激活通过增强HMGCS2介导的溃疡性结肠炎中的酮生成来促进杯状细胞分化
Biochim Biophys Acta Mol Basis Dis. 2024 Dec;1870(8):167477.doi: 10.1016/j.bbadis.2024.167477. Epub 2024 Aug 22. TRPML1 ameliorates seizures-related neuronal injury by regulating autophagy and lysosomal biogenesis via Ca2+/TFEB signaling pathway TRPML1通过Ca2+/TFEB信号通路调节自噬和溶酶体生物合成，改善癫痫发作相关的神经元损伤
Eur J Pharmacol. 2024 Nov 5:982:176933.doi: 10.1016/j.ejphar.2024.176933. Epub 2024 Aug 23. Up-regulation of IL-1β and sPLA2-III in the medial prefrontal cortex contributes to orofacial and somatic hyperalgesia induced by malocclusion via glial-neuron crosstalk 内侧前额叶皮层IL-1β和sPLA2-III的上调通过神经胶质神经元串扰导致错颌引起的口面部和躯体痛觉过敏
Microb Cell Fact. 2024 Oct 18;23(1):284.doi: 10.1186/s12934-024-02534-7. The signal peptide of BmNPV GP64 activates the ERAD pathway to regulate heterogeneous secretory protein expression BmNPV GP64信号肽激活ERAD通路调节异质性分泌蛋白表达
Cell Rep Med. 2024 Oct 15;5(10):101731.doi: 10.1016/j.xcrm.2024.101731. Epub 2024 Sep 19. Reprograming immunosuppressive microenvironment by eIF4G1 targeting to eradicate pancreatic ductal adenocarcinoma 通过靶向eIF4G1重新编程免疫抑制微环境以根除胰腺导管腺癌 (IF:14.3).
Cell Death Dis. 2024 Oct 14;15(10):748.doi: 10.1038/s41419-024-07121-7. GRHL2 regulates keratinocyte EMT-MET dynamics and scar formation during cutaneous wound healing GRHL2调节皮肤伤口愈合过程中角质形成细胞EMT-MET动力学和瘢痕形成 (IF:8.1).
J Control Release. 2024 Oct:374:293-311.doi: 10.1016/j.jconrel.2024.08.019. Epub 2024 Aug 21. Enhanced delivery of CRISPR/Cas9 system based on biomimetic nanoparticles for hepatitis B virus therapy (IF:11.467). 基于仿生纳米颗粒的CRISPR/Cas9系统增强递送用于乙型肝炎病毒治疗
Cell Mol Life Sci. 2024 Oct 5;81(1):422.doi: 10.1007/s00018-024-05452-4. SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus (IF:9.207). SENP1介导锌诱导的Lys-409处的ZnT6脱SUMO化，参与高尔基体锌代谢的调节
Cell Rep. 2024 Sep 24;43(9):114691.doi: 10.1016/j.celrep.2024.114691. Epub 2024 Sep 3. Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia (IF:8.8). Nogo-B抑制促进胆固醇代谢以降低高胆固醇血症
Cell Biochem Biophys. 2024 Sep 22.doi: 10.1007/s12013-024-01530-3. Inhibition of FABP4 Ameliorates IL-13-Induced Inflammatory Response and Barrier Dysfunction in Nasal Mucosal Epithelial Cells through the Regulation of Ferroptosis 抑制FABP4通过调节铁下垂改善IL-13诱导的鼻粘膜上皮细胞炎症反应和屏障功能障碍
