Cell Calcium. 2026 Apr 19:135:103137.doi: 10.1016/j.ceca.2026.103137. TRPC1 channel modulates mechanical stretch-induced bone marrow mesenchymal stem cell proliferation through Ca2+-dependent ERK1/2 activation TRPC1通道通过Ca2+依赖的ERK1/2激活调节机械拉伸诱导的骨髓间充质干细胞增殖
Sci Rep. 2026 Apr 9.doi: 10.1038/s41598-026-46857-4. CD204 regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following intracerebral hemorrhage CD204调节小胶质细胞/巨噬细胞M1/M2极化，并缓解脑出血后的神经炎症
Int J Radiat Oncol Biol Phys. 2026 Apr 5:S0360-3016(26)00521-3.doi: 10.1016/j.ijrobp.2026.03.037. Alternative End Joining Dependency Imposed by miR-21-5p Defines Radiation Resistance and a Targetable Vulnerability in Oral Squamous Cell Carcinoma miR-21-5p强加的替代末端连接依赖性定义了口腔鳞状细胞癌的辐射抗性和可靶向的脆弱性 (IF:6.5).
Cell Death Dis. 2026 Mar 30.doi: 10.1038/s41419-026-08666-5. AKR1C3-PKM2-oxidative phosphorylation axis drives prostate cancer radioresistance via UBE2T upregulation AKR1C3–PKM2–氧化磷酸化轴通过上调UBE2T来驱动前列腺癌的放射抗性(IF:9.6).
Pharmaceuticals (Basel). 2026 Mar 27;19(4):540.doi: 10.3390/ph19040540. Identification of Dopamine D2 Receptor as a Direct Target of Salidroside and Tyrosol by Integrated Transcriptomic and Biophysical Approaches 通过转录组学和生物物理学综合方法鉴定多巴胺D2受体为红景天苷和酪醇的直接靶点 (IF:5.68).
Animals (Basel). 2026 Mar 26;16(7):1017.doi: 10.3390/ani16071017. CircCOPS8 Inhibits the Proliferation of Buffalo Myoblasts by Binding to IGF2BP3 and Promoting ATR Gene Expression CircCOPS8通过结合IGF2BP3并促进ATR基因表达来抑制水牛成肌细胞的增殖
J Transl Med. 2026 Mar 26;24(1):630.doi: 10.1186/s12967-026-08050-z. CPNE1: A novel therapeutic target for myopia progression – from genetic GWAS discovery to functional validation in vitro and vivo CPNE1：近视进展的新型治疗靶点——从遗传全基因组关联研究（GWAS）发现到体内外功能验证 (IF:7.5).
Cell Chem Biol. 2026 Mar 20:S2451-9456(26)00071-1.doi: 10.1016/j.chembiol.2026.03.001. Engineered pistol ribozymes selectively target KRAS G12V with enhanced efficacy by capping modification 通过加帽修饰，工程化手枪状核酶能以更高的效率选择性地靶向KRAS G12V (IF:7.2).
Genomics. 2026 Mar;118(2):111194.doi: 10.1016/j.ygeno.2026.111194. Epub 2026 Jan 5. The translation landscape revealed the novel micropeptides involved in myogenic differentiation of goat skeletal muscle satellite cells
Viruses. 2026 Mar 5;18(3):323.doi: 10.3390/v18030323. Tree Shrew Genome-Wide CRISPR Screen Identifies RNF6 as a Proviral Host Factor for Zika Virus Replication in Brain Microvascular Endothelial Cells 树鼩全基因组CRISPR筛选鉴定出RNF6是寨卡病毒在脑微血管内皮细胞中复制的病毒前体宿主因子
