Nat Commun. 2024 Aug 10;15(1):6845.doi: 10.1038/s41467-024-51352-3. (IF:14.700).
2024-08-10Nat Commun. 2024 Aug 10;15(1):6845.doi: 10.1038/s41467-024-51352-3. Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage (IF:14.700).肠Nogo-B通过与内质网上的胰高血糖素原结合来抑制PCSK1切割,从而降低GLP1水平