Nat Biotechnol. 2025 Apr 21.doi: 10.1038/s41587-025-02641-9. Online ahead of print. QBEmax is a sequence-permuted and internally protected base editor QBEmax是一个序列置换和内部保护的碱基编辑器 (IF:33.1).
Microbiome. 2025 Mar 17;13(1):75.doi: 10.1186/s40168-025-02047-4. Short-term and long-term high-fat diet promote metabolic disorder through reprogramming mRNA m6A in white adipose tissue by gut microbiota 短期和长期高脂肪饮食通过肠道微生物群对白色脂肪组织中m6A mRNA的重编程促进代谢紊乱 (IF:13.800).
Cell. 2025 Feb 20;188(4):1119-1136.e23.doi: 10.1016/j.cell.2024.12.010. Epub 2025 Jan 17. Hyperacute rejection-engineered oncolytic virus for interventional clinical trial in refractory cancer patients 癌症难治性患者超急性排斥反应工程溶瘤病毒介入临床试验 (IF:66.850).
Adv Sci (Weinh). 2025 Jan 31:e2413333.doi: 10.1002/advs.202413333. LncRNA TUG1 Repressed Angiogenesis by Promoting the Ubiquitination of HuR and Inhibiting Its Nuclear Translocation in Cerebral Ischemic Reperfusion Injury LncRNA TUG1通过促进HuR的泛素化和抑制其在脑缺血再灌注损伤中的核转位来抑制血管生成 (IF:14.3).
Adv Sci (Weinh). 2024 Sep 19:e2308990.doi: 10.1002/advs.202308990. Online ahead of print. Gasdermin C promotes Stemness and Immune Evasion in Pancreatic Cancer via Pyroptosis-Independent Mechanism Gasdermin C (IF:15.100).通过与Pyroptosis无关的机制促进癌症胰腺癌的应激和免疫逃避
EMBO Mol Med. 2024 Sep;16(9):2146-2169.doi: 10.1038/s44321-024-00117-y. Epub 2024 Aug 15. Histidine-rich glycoprotein modulates neutrophils and thrombolysis-associated hemorrhagic transformation (IF:13.547).富含组氨酸的糖蛋白调节中性粒细胞和溶栓相关的出血转化
Autophagy. 2024 Sep 3:1-14.doi: 10.1080/15548627.2024.2395158. Online ahead of print. ABHD8 antagonizes inflammation by facilitating chaperone-mediated autophagy-mediated degradation of NLRP3 (IF:14.600). ABHD8通过促进伴侣介导的自噬介导的NLRP3降解来拮抗炎症
Nat Commun. 2024 Aug 13;15(1):6964.doi: 10.1038/s41467-024-51192-1. SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia 严重急性呼吸系统综合征冠状病毒2型N蛋白诱导的Dicer、XPO5、SRSF3和hnRNPA3下调导致肺炎(IF:14.7).
Cell Metab. 2024 Jun 4;36(6):1287-1301.e7.doi: 10.1016/j.cmet.2024.05.005. The browning and mobilization of subcutaneous white adipose tissue supports efficient skin repair (IF31.3737). 皮下白色脂肪组织的褐变和支持有效的皮肤修复
Small Methods. 2024 Jan 2:e2301310.doi: 10.1002/smtd.202301310. Online ahead of print. An Inducible CRISPR-dCas9-Based Transcriptional Repression System for Cancer Therapy 一种用于癌症治疗的基于诱导CRISPR-dCas9的转录抑制系统(IF:25.367).
