订单满1000元，免运费
EntransterTM-H4000是英格恩生物公司研发合成的纳米聚合物转染试剂，该试剂采用纳米技术合成，是最新一代非病毒转染试剂。由于纳米技术的应用，EntransterTM-H4000在细胞转染过程中，表现了卓越的低毒、高效的性能。
本品推荐用于常规DNA以及长片段（>1kb）的mRNA等RNA的转染。
常规DNA以及长片段（>1kb）的mRNA等RNA的转染。
| 人源，遗传变异细胞和正常组织来源细胞 | 人源，肿瘤细胞 | 其他动物来源细胞 |
| AsPC-1，BNL CL2，HEK293，CFPEo，HUVEC，HLMEC，H-MVEC，MRC-5，HCS-2/8，HLF，D407，H9C2，SMC | A549，HuH-7，HepG2，HME4，A375，Hep-2，SW480，SKOV-3，IGROV1，K562，Jurkat，MCF7，MDA-MB-231，ZR-75-1，TCA8113，Eca-109，SGC-7901，HeLa，SiHa，Ca Ski，CaCo2，SAOS-2，PC-3，SHEP | B16BL6，B16F10，C2C12，C6，CHO，COS-7，CV-1，BHK-21，MDCK，PC12，BAEC，MLE-12，MLE-15，Neuro2A，PGHAM-1，RAW 264.7，EL-4，L929，LLC，3LL，NIH 3T3 |
各细胞系详细转染效率情况
| 细胞名称 | 来源 | 转染效率(%) |
| AsPC-1 | 人源，胰脏细胞 | 80% |
| BNL CL2 | 人源，胚胎肾细胞 | 70% |
| HEK 293 | 人源，胚胎肾细胞 | 90% |
| CFPEo | 人源，气管上皮细胞 | 50% |
| HUVEC | 人源，脐带静脉内皮状细胞 | 55% |
| HLMEC | 人源，肺血管内皮细胞 | 60% |
| H-MVEC | 人源，微血管内皮细胞 | 50% |
| MRC-5 | 人源，胚胎肺细胞 | 75% |
| HCS-2/8 | 人源，软骨样细胞 | 40% |
| HLF | 人源，肺成纤维细胞 | 65% |
| D 407 | 人源，视网膜色素上皮细胞 | 60% |
| A549 | 人源，肺癌细胞 | 90% |
| HuH-7 | 人源，肝癌细胞 | 63% |
| HepG2 | 人源，肝癌细胞 | 30% |
| HME4 | 人源，黑色素瘤细胞 | 90% |
| A375 | 人源，黑色素瘤细胞 | 70% |
| Hep-2 | 人源，喉癌细胞 | 70% |
| SAOS-2 | 人源，骨肉瘤细胞 | 50% |
| SKOV-3 | 人源，卵巢腺癌细胞 | 60% |
| IGROV1 | 人源，卵巢癌细胞 | 20% |
| K562 | 人源，慢性白血病细胞 | 30% |
| Jurkat | 人源，T淋巴细胞白血病细胞 | 45% |
| MCF7 | 人源，乳腺癌细胞 | 55% |
| MDA-MB-231 | 人源，乳腺癌细胞 | 70% |
| ZR-75-1 | 人源，乳腺癌细胞 | 70% |
| TCA8113 | 人源，舌鳞癌细胞 | 90% |
| Eca-109 | 人源，胃腺癌细胞 | 57% |
| SGC-7901 | 人源，胃腺癌细胞 | 48% |
| BGC-823 | 人源，胃腺癌细胞 | 60% |
| Panc-1 | 人源，胰腺癌细胞 | 40% |
| HeLa | 人源，宫颈癌细胞 | 80% |
| SiHa | 人源，宫颈癌细胞 | 70% |
| Ca Ski | 人源，宫颈表皮样癌细胞 | 80% |
| CaCo2 | 人源，结肠癌上皮细胞 | 30% |
| SW480 | 人源，结肠腺癌细胞 | 80% |
| PC-3 | 人源，前列腺癌细胞 | 30% |
| SHEP | 人源，神经母细胞瘤细胞 | 70% |
| B16BL6 | 小鼠，黑色素瘤细胞 | 90% |
| B16F10 | 小鼠，黑色素瘤细胞 | 80% |
| C2C12 | 小鼠，胚胎肌原细胞 | 30% |
| C6 | 大鼠，脑胶质瘤细胞 | 60% |
| CHO | 中国仓鼠，卵巢细胞 | 90% |
| COS-7 | 猴SV40转化肾细胞 | 80% |
| CV-1 | 非洲绿猴肾细胞 | 70% |
| BHK-21 | 仓鼠，肾细胞 | 80% |
| MDCK | 犬，肾上皮细胞 | 30% |
| PC12 | 大鼠，肾上腺嗜铬细胞瘤细胞 | 33% |
| BAEC | 牛，动脉内皮细胞 | 50% |
| MLE-12 | 小鼠，肺上皮细胞 | 70% |
| MLE-15 | 小鼠，肺上皮细胞 | 70% |
| Neuro2A | 小鼠，成神经瘤细胞 | 70% |
| PGHAM-1 | 仓鼠，胰腺癌细胞 | 90% |
| RAW 264.7 | 小鼠，巨噬细胞 | 15% |
| EL-4 | 小鼠，胸腺瘤细胞 | 75% |
| L929 | 小鼠，成纤维肉瘤细胞 | 60% |
| LLC | 小鼠，路易斯肺癌细胞 | 75% |
| 3LL | 小鼠，路易斯肺癌细胞 | 65% |
| NIH 3T3 | 小鼠，胚胎纤维原细胞 | 40% |
| P19 | 小鼠，胚胎肉瘤细胞 | 60% |
用法用量和常见的脂质体试剂完全一样，可不改流程方法更换试剂 转染效率更高，每支节省1000元以上，可根据需要定做500ml以上大包装，可批量定制产品。
Commun Biol . 2025 May 29;8(1):827.doi: 10.1038/s42003-025-08290-7. A new type of Caspase-1 upon recognizing bacteria inhibits GSDME-dependent histone modification and NF-κB signaling 一种新型的Caspase-1在识别细菌时抑制GSDME依赖的组蛋白修饰和NF-κB信号传导 (IF:5.2).
Insects. 2025 May 21;16(5):544.doi: 10.3390/insects16050544. 20-Hydroxyecdysone Modulates Bmp53-Mediated Apoptosis Regulation by Suppressing Mdm2-like-Dependent Ubiquitination in Silkworm, Bombyx mori
PLoS Biol. 2025 Apr 1;23(4):e3003047.doi: 10.1371/journal.pbio.3003047. eCollection 2025 Apr. Mdga2 deficiency leads to an aberrant activation of BDNF/TrkB signaling that underlies autism-relevant synaptic and behavioral changes in mice Mdga2缺乏导致BDNF/TrkB信号的异常激活，这是小鼠自闭症相关突触和行为变化的基础(IF:9.8).
Bull Entomol Res. 2025 Mar 24:1-14.doi: 10.1017/S000748532500015X. BmWARS inhibits BmNPV infection via the PI3K-Akt pathway BmWARS通过PI3K-Akt途径抑制BmNPV感染
J Invertebr Pathol. 2025 Feb 21:210:108289.doi: 10.1016/j.jip.2025.108289. Characterization and functional analysis of the small heat shock protein HSP19.5 in Bombyx mori in response to Nosema bombycis infection 小分子热休克蛋白HSP19.5的特性和功能分析对家蚕微孢子虫感染的反应
Cancer Cell Int. 2025 Jan 13;25(1):10.doi: 10.1186/s12935-025-03638-9.Heterogeneous nuclear ribonucleoprotein C promotes non-small cell lung cancer progression by enhancing XB130 mRNA stability and translation (IF:5.3).异质性核核糖核蛋白C通过增强XB130mRNA的稳定性和翻译促进非小细胞肺癌的进展
J Virol. 2024 Nov 27:e0151124.doi: 10.1128/jvi.01511-24. Unraveling dual fusion mechanisms in BmNPV GP64: critical roles of CARC motifs and signal peptide retention 解开BmNPV GP64中的双重融合机制：CARC基序和信号肽保留的关键作用
Mar Biotechnol (NY). 2024 Nov 27;27(1):11.doi: 10.1007/s10126-024-10379-9. A Zinc Uptake Transporter ZIP1-II Is Involved in Zinc Accumulation in the Hepatopancreas of Pacific Oyster Crassostrea gigas 锌摄取转运蛋白ZIP1-II参与太平洋牡蛎肝胰腺中锌的积累
Microb Cell Fact. 2024 Oct 18;23(1):284.doi: 10.1186/s12934-024-02534-7. The signal peptide of BmNPV GP64 activates the ERAD pathway to regulate heterogeneous secretory protein expression BmNPV GP64信号肽激活ERAD通路调节异质性分泌蛋白表达
Virology. 2024 Sep:597:110147.doi: 10.1016/j.virol.2024.110147. Epub 2024 Jun 19. Unveiling non-classical glycosylation patterns in Bombyx mori nucleopolyhedrovirus GP64: Insights into viral entry and fusion 揭示家蚕核型多角体病毒GP64的非经典糖基化模式：对病毒进入和融合的见解
Front Pharmacol. 2024 Sep 6:15:1439497.doi: 10.3389/fphar.2024.1439497. eCollection 2024. The lncRNA CADM2-AS1 promotes gastric cancer metastasis by binding with miR-5047 and activating NOTCH4 translation lncRNA CADM2-AS1通过与miR-5047结合并激活NOTCH4翻译来促进癌症转移 (IF:5.6).
Biol Res. 2024 Sep 9;57(1):64.doi: 10.1186/s40659-024-00544-8. Mouse testicular macrophages can independently produce testosterone and are regulated by Cebpb 小鼠睾丸巨噬细胞可以独立产生睾酮，并受Cebpb的调节
J Virol Methods. 2024 Jun:327:114933.doi: 10.1016/j.jviromet.2024.114933. Epub 2024 Apr 4. Intracellular localized heterogeneous protein franking by a transmembrane domain of GP64 is sufficient to be assembled on budded virions of Bombyx mori nucleopolyhedrovirus GP64跨膜结构域在细胞内定位的异质蛋白franking足以在家蚕核型多角体病毒的芽状病毒颗粒上组装
Int J Biol Macromol. 2024 May;266(Pt 1):131197.doi: 10.1016/j.ijbiomac.2024.131197. Epub 2024 Mar 28. Bombyx mori triose-phosphate transporter protein inhibits Bombyx mori nucleopolyhedrovirus infection by reducing the cell glycolysis pathway 家蚕三糖磷酸转运蛋白通过减少细胞糖酵解途径抑制家蚕核型多角体病毒感染
Invest Ophthalmol Vis Sci. 2024 Apr 1;65(4):1.doi: 10.1167/iovs.65.4.1. Identification of Novel FZD4 Mutations in Familial Exudative Vitreoretinopathy and Investigating the Pathogenic Mechanisms of FZD4 Mutations 家族性渗出性玻璃体视网膜病中新型FZD4突变的鉴定及FZD4突变致病机制的研究
Int Immunopharmacol. 2024 Apr 20:131:111864.doi: 10.1016/j.intimp.2024.111864. Epub 2024 Mar 13. miR-186-5p improves alveolar epithelial barrier function by targeting the wnt5a/β-catenin signaling pathway in sepsis-acute lung injury miR-186-5p通过靶向wnt5a/β-catenin信号通路改善脓毒症急性肺损伤肺泡上皮屏障功能
J Exp Clin Cancer Res. 2024 Apr 23;43(1):123.doi: 10.1186/s13046-024-03048-1. Tumor-suppressive miR-4732-3p is sorted into fucosylated exosome by hnRNPK to avoid the inhibition of lung cancer progression (IF:12.658).肿瘤抑制性miR-4732-3p通过hnRNPK分类为岩藻糖基外泌体，以避免对肺癌癌症进展的抑制
Mol Genet Genomics. 2024 Mar 13;299(1):32.doi: 10.1007/s00438-024-02128-3. Characterization of a novel heterozygous frameshift variant in NDP gene that causes familial exudative vitreoretinopathy in female patients 导致女性家族性渗出性玻璃体视网膜病变的NDP基因新型杂合移码变异的特征
Invest Ophthalmol Vis Sci. 2024 Mar 5;65(3):31.doi: 10.1167/iovs.65.3.31. Investigating the Impact of Dimer Interface Mutations on Norrin’s Secretion and Norrin/β-Catenin Pathway Activation 二聚体界面突变对Norrin分泌和Norrin/β-Catenin通路激活的影响
Dev Comp Immunol. 2024 Mar:152:105114.doi: 10.1016/j.dci.2023.105114. Epub 2023 Dec 13. Ras3 in Bombyx mori with antiviral function against B. mori nucleopolyhedrovirus 家蚕Ras3对家蚕核型多角体病毒具有抗病毒作用
FASEB J. 2024 Feb 29;38(4):e23493.doi: 10.1096/fj.202302387R. Deciphering a crucial dimeric interface governing Norrin dimerization and the pathogenesis of familial exudative vitreoretinopathy 解读Norrin二聚化的关键二聚体界面和家族性渗出性玻璃体视网膜病变的发病机制
Int J Biol Macromol. 2024 Feb;258(Pt 1):128570.doi: 10.1016/j.ijbiomac.2023.128570. Epub 2023 Dec 12. Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation (IF:8.2. CTNNB1 C末端的移码变异通过AXIN1介导的泛素-蛋白酶体降解缩合引起家族性渗出性玻璃体视网膜病变
Cell Commun Signal. 2024 Feb 1;22(1):93.doi: 10.1186/s12964-024-01497-x. Mechanosensitive channel of large conductance enhances the mechanical stretching-induced upregulation of glycolysis and oxidative metabolism in Schwann cells (IF:7.525). 大电导的机械敏感通道增强了机械拉伸诱导的雪旺氏细胞糖酵解和氧化代谢的上调
Small Methods. 2024 Jan 2:e2301310.doi: 10.1002/smtd.202301310. Online ahead of print. An Inducible CRISPR-dCas9-Based Transcriptional Repression System for Cancer Therapy 一种用于癌症治疗的基于诱导CRISPR-dCas9的转录抑制系统(IF:25.367).
Cell Death Dis. 2023 Nov 3;14(11):716.doi: 10.1038/s41419-023-06238-5. Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC CTNNB1新截短变异体引起家族性渗出性玻璃体视网膜病变
Mol Neurobiol. 2023 Nov 22.doi: 10.1007/s12035-023-03808-8. Mol Neurobiol . 2023 Nov 22. doi: 10.1007/s12035-023-03808-8. Online ahead of print. GSK-126 Attenuates Cell Apoptosis in Ischemic Brain Injury by Modulating the EZH2-H3K27me3-Bcl2l1 Axis GSK-126通过调节EZH2-H3K27me3-Bcl2l1轴减轻缺血性脑损伤中的细胞凋亡
Int J Biol Macromol. 2023 Sep 7:126801.doi: 10.1016/j.ijbiomac.2023.126801. Online ahead of print. Neddylation-dependent Neddylation-dependent LSD1 destabilization inhibits the stemness and chemoresistance of gastric cancer LSD1失稳抑制癌症的干燥和化疗耐药性
Gene. 2023 Sep 25:881:147626.doi: 10.1016/j.gene.2023.147626. Epub 2023 Jul 8. BmINR and BmAC6 genes involve in diapause regulation via the insulin/IGF signaling pathway in the silkworm (Bombyx mori) 家蚕BmINR和BmAC6基因通过胰岛素/IGF信号通路参与滞育调控
Sci Adv. 2023 Jul 21;9(29):eadf7858.doi: 10.1126/sciadv.adf7858. Epub 2023 Jul 21. Engineered exosomes reprogram Gli1+ cells in vivo to prevent calcification of vascular grafts and autologous pathological vessels 工程外泌体在体内重新编程Gli1+细胞，以防止血管移植物和自体病理血管钙化 (IF:14.98).
Mol Biol Rep. 2023 Jun;50(6):5295-5306.doi: 10.1007/s11033-023-08489-z. Epub 2023 May 6. m6A-dependent mevalonate kinase in juvenile hormone synthesis pathway regulates the diapause process of bivoltine silkworm (Bombyx mori) m6A依赖性甲羟戊酸激酶在幼激素合成途径中调节二伏蚕滞育过程
Food Sci Biotechnol. 2023 Jun 19;33(2):465-474.doi: 10.1007/s10068-023-01358-2. eCollection 2024 Jan. A novel protein extracted from Hemerocallis citrina Borani inhibits hepatocellular carcinoma cell proliferation by regulating mitochondria-dependent apoptosis and aerobic glycolysis 从萱草中提取的一种新蛋白通过调节线粒体依赖性细胞凋亡和抑制肝癌细胞增殖
Insects. 2023 Apr 5;14(4):362.doi: 10.3390/insects14040362. Determination of Key Components in the Bombyx mori p53 Apoptosis Regulation Network Using Y2H-Seq Y2H-Seq法测定家蚕p53细胞凋亡调控网络的关键成分
Oncol Lett. 2023 Feb 28;25(4):143.doi: 10.3892/ol.2023.13729. eCollection 2023 Apr. Effects of Helicobacter pylori on the expression of the FTO gene and its biological role in gastric cancer 幽门螺杆菌对FTO基因表达的影响及其在癌症中的生物学作用
J Med Genet. 2023 Feb;60(2):174-182.doi: 10.1136/jmedgenet-2021-108259. Epub 2022 Mar 31. Novel truncating variants in CTNNB1 cause familial exudative vitreoretinopathy CTNNB1新截短变异体引起家族性渗出性玻璃体视网膜病变
Biochem Biophys Res Commun. 2023 Jan 8:639:36-45.doi: 10.1016/j.bbrc.2022.11.067. Epub 2022 Nov 24. Silencing long non-coding RNA SNHG3 repairs the dysfunction of pulmonary microvascular endothelial barrier by regulating miR-186-5p/Wnt axis 沉默长非编码RNA SNHG3通过调节miR-186-5p/Wnt轴修复肺微血管内皮屏障功能障碍
Arch Pharm Res. 2023 Jan;46(1):44-58.doi: 10.1007/s12272-023-01426-5. Epub 2023 Jan 6. MEKs/ERKs-mediated FBXO1/E2Fs interaction interference modulates G1/S cell cycle transition and cancer cell proliferation MEKs/ERKs介导的FBXO1/E2Fs相互作用干扰调节G1/S细胞周期转变和癌症细胞增殖
Front Surg. 2023 Jan 6:9:1062659.doi: 10.3389/fsurg.2022.1062659. eCollection 2022. Classification of the mitochondrial ribosomal protein-associated molecular subtypes and identified a serological diagnostic biomarker in hepatocellular carcinoma 肝细胞癌线粒体核糖体蛋白相关分子亚型的分类及血清学诊断标志物的鉴定
Adipocyte. 2022 Dec;11(1):477-486.doi: 10.1080/21623945.2022.2107786. (IF3.553) MAPKs/AP-1, not NF-κB, is responsible for MCP-1 production in TNF-α-activated adipocytes 激活的脂肪细胞中MCP-1的产生
Int Immunopharmacol. 2022 Dec;113(Pt A):109312.doi: 10.1016/j.intimp.2022.109312. Epub 2022 Oct 14. Resibufogenin, one of bufadienolides in toad venom, suppresses LPS-induced inflammation via inhibiting NF-κB and AP-1 pathways CDK1通过抑制∆Np63α介导的转录调控促进头颈部鳞状细胞癌细胞的上皮-间充质过渡和迁移
Protein Expr Purif. 2022 Dec:200:106156.doi: 10.1016/j.pep.2022.106156. Epub 2022 Aug 18. The cytoplasmic tail substitution increases the assembly efficiency of Ebola virus glycoprotein on the budded virus of Bombyx mori nucleopolyhedrovirus 细胞质尾部置换提高了埃博拉病毒糖蛋白在家蚕核型多角体病毒芽状病毒上的组装效率
Front Mol Neurosci. 2022 Dec 8:15:1034766.doi: 10.3389/fnmol.2022.1034766. eCollection 2022. Nucleosome assembly protein 1-like 5 alleviates Alzheimer’s disease-like pathological characteristics in a cell model 核小体组装蛋白1-like 5在细胞模型中缓解阿尔茨海默病样病理特征
Microbiol Spectr. 2022 Aug 31;10(4):e0191322.doi: 10.1128/spectrum.01913-22. Epub 2022 Aug 8. (IF9.043) The Bombyx mori Nucleopolyhedrovirus GP64 Retains the Transmembrane Helix of Signal Peptide to Contribute to Secretion across the Cytomembrane 家蚕核多角体病毒GP64保留信号肽的跨膜螺旋以促进跨细胞膜分泌
Fish Shellfish Immunol. 2022 Aug:127:129-139.doi: 10.1016/j.fsi.2022.05.057. Epub 2022 Jun 14. A RAC-alpha serine/threonine-protein kinase (CgAKT1) involved in the synthesis of CgIFNLP in oyster Crassostrea gigas RACα-丝氨酸/苏氨酸蛋白激酶（CgAKT1）参与牡蛎CgIFNLP的合成
Research (Wash D C) . 2022 Jul 19;2022:9826426. doi: 10.34133/2022/9826426. eCollection 2022. Programming of Regulatory T Cells In Situ for Nerve Regeneration and Long-Term Patency of Vascular Grafts. (IF:11.036).
Int J Mol Sci. 2022 Jul 2;23(13):7385.doi: 10.3390/ijms23137385. (IF6.208) CDK1 Promotes Epithelial-Mesenchymal Transition and Migration of Head and Neck Squamous Carcinoma Cells by Repressing ∆Np63α-Mediated Transcriptional Regulation CDK1通过抑制∆Np63α介导的转录调节促进头颈部鳞状细胞的上皮-间充质转移和迁移
J Med Genet. 2022 Mar 31;jmedgenet-2021-108259. doi: 10.1136/jmedgenet-2021-108259. Online ahead of print. Novel truncating variants in CTNNB1 cause familial exudative vitreoretinopathy (IF:6.318).
STAR Protoc. 2022 Mar 15;3(2):101239.doi: 10.1016/j.xpro.2022.101239. eCollection 2022 Jun 17. Measuring Laplace pressure and imaging the actin cortex during cytokinesis in cultured cells 培养细胞胞质分裂过程中拉普拉斯压力的测量和肌动蛋白皮层的成像
Food Funct. 2022 Mar 7;13(5):2913-2924. doi: 10.1039/d1fo02755g. and bone formation via activating the Wnt/β-catenin signaling pathway (IF:5.396).
Ticks Tick Borne Dis. 2022 Jan 17;13(3):101906.Differential characteristics of mammalian and tick-derived promoters to trigger protein expression in transfected tick cell lines.
Dev Comp Immunol. 2022 Jun;131:104382. doi: 10.1016/j.dci.2022.104382. Epub 2022 Mar 1. A cypovirus encoded microRNA negatively regulates the NF-κB pathway to enhance viral multiplication in Silkworm, Bombyx mori
Exp Mol Med.2022 Jan;54(1):35-46.doi: 10.1038/s12276-021-00721-9.Epub 2022 Jan 12. FBXW7-mediated ERK3 degradation regulates the proliferation of lung cancer cells.
Nutr Cancer. 2022;74(1):333-345.doi: 10.1080/01635581.2021.1882508. Epub 2021 Feb 5. TKP, a Serine Protease from Trichosanthes kirilowii, Inhibits Cell Proliferation by Blocking Aerobic Glycolysis in Hepatocellular Carcinoma Cells 天花粉丝氨酸蛋白酶TKP通过阻断肝细胞癌细胞的有氧糖酵解抑制细胞增殖
iScience. 2022 Feb 21;25(3):103949. doi: 10.1016/j.isci.2022.103949. eCollection 2022 Mar 18. Long noncoding RNA Lnc-DIF inhibits bone formation by sequestering miR-489-3p (IF:6.007).
Eur J Ophthalmol. 2022 Jan 17;11206721221074209. doi: 10.1177/11206721221074209. Online ahead of print. Whole-Exome Sequencing Reveals Novel NDP Variants in X-Linked Familial Exudative Vitreoretinopathy
J Anim Sci Biotechnol. 2021 Dec 13;12(1):120. doi: 10.1186/s40104-021-00639-2. Transcriptome sequencing analysis for the identification of stable lncRNAs associated with bovine Staphylococcus aureus mastitis (IF:5.032).
Arch Pharm Res. 2021 Dec;44(12):1091-1108.doi: 10.1007/s12272-021-01358-y. Epub 2021 Nov 9. Kaempferol sensitizes cell proliferation inhibition in oxaliplatin-resistant colon cancer cells 山奈酚对奥沙利铂耐药结肠癌癌症细胞增殖抑制的敏感性
Insect Mol Biol. 2021 Dec;30(6):552-565.doi: 10.1111/imb.12725. Epub 2021 Jul 30. Functional analysis of a putative Bombyx mori cypovirus miRNA BmCPV-miR-10 and its effect on virus replication 家蚕cypovirus miRNA BmCPV-miR-10的功能分析及其对病毒复制的影响
Biomed Pharmacother. 2021 Oct;142:112056.doi:10.1016/j.biopha.2021.112056. Epub 2021 Aug 23. Dysregulation of miR-342-3p in plasma exosomes derived from convalescent AMI patients and its consequences on cardiac repair恢复期AMI患者血浆外小体中miR-342-3p的失调及其对心脏修复的影响
Fish Shellfish Immunol. 2021 Dec;119:173-181. doi: 10.1016/j.fsi.2021.09.016. Epub 2021 Oct 2. Identification and characterization of an apoptosis-inducing factor 1 involved in apoptosis and immune defense of oyster, Crassostrea gigas
Photodermatol Photoimmunol Photomed. 2021 Sep;37(5):395-403.doi: 10.1111/phpp.12670. Epub 2021 Feb 23. Ultraviolet B irradiation up-regulates MM1 and induces photoageing of the epidermis 紫外线B照射上调MM1并诱导表皮光老化
Anal Chem. 2021 Aug 31;93(34):11775-11784.doi: 10.1021/acs.analchem.1c02197. Epub 2021 Aug 19. Facile Method for Specifically Sensing Sphingomyelinase in Cells and Human Urine Based on a Ratiometric Fluorescent Nanoliposome Probe 基于定量荧光纳米脂质体探针的简便特异性检测细胞和人尿液中鞘氨醇酶的方法
Cell Biosci. 2021 Aug 4;11(1):156.doi: 10.1186/s13578-021-00669-3. Modaline sulfate promotes Oct4 expression and maintains self-renewal and pluripotency of stem cells through JAK/STAT3 and Wnt signaling pathways通过JAKSTAT3和Wnt检测干细胞
Front Physiol. 2021 Aug 4;12:663482.doi:10.3389/fphys.2021.663482. eCollection 2021. Two Putative Cypovirus-Encoded miRNAs Co-regulate the Host Gene of GTP-Binding Nuclear Protein Ran and Facilitate Virus ReplicationmiRNA共同调节宿主基因GTP结合核蛋白Ran的表达
J Cell Mol Med. 2021 Jul;25(13):6242-6257.doi: 10.1111/jcmm.16579. Epub 2021 Jun 15. MACF1 alleviates aging-related osteoporosis via HES1 MACF1通过HES1缓解与衰老相关的骨质疏松症
Cell Death Differ. 2021 Jul;28(7):2160-2178.doi:10.1038/s41418-021-00744-9. Epub 2021 Mar 4. MACF1 promotes osteoblast differentiation by sequestering repressors in cytoplasmMACF1通过隔离促进成骨细胞分化
Genet Test Mol Biomarkers. 2021 Jun;25(6):399-404.doi: 10.1089/gtmb.2021.0019. Epub 2021 Jun 2.Whole-Exome Sequencing Reveals Novel TSPAN12 Variants in Autosomal Dominant Familial Exudative Vitreoretinopathy
Front Pharmacol. 2021 Jun 14;12:696729.doi:10.3389/fphar.2021.696729. eCollection 2021. Forsythiasides-Rich Extract From Forsythiae Fructus Inhibits Mast Cell Degranulation by Enhancing Mitochondrial Ca 2+ Uptake连翘抑制肥大细胞生长线粒体钙摄取
Biochem Pharmacol. 2021 Apr;186:114476.doi:10.1016/j.bcp.2021.114476. Epub 2021 Feb 17. Aloe-emodin, a naturally occurring anthraquinone, is a highly potent mast cell stabilizer through activating mitochondrial calcium uniporter芦荟大黄素
Gene. 2021 Apr 20;777:145450.doi: 10.1016/j.gene.2021.145450. Epub 2021 Jan 29. A 14-amino acids deletion in BmShadow results to non-moult on the 2nd instar in the bivoltine silkworm, Bombyx moriBmShadow中14个氨基酸的缺失导致二伏家蚕2龄时不蜕皮
FEBS Open Bio. 2021 Mar;11(3):890-897.doi: 10.1002/2211-5463.13109. Epub 2021 Feb 19. Pin1 and JNK1 cooperatively modulate TAp63γ Pin1和JNK1协同调节TAp63γ
Curr Microbiol. 2021 Feb;78(2):490-501.doi: 10.1007/s00284-020-02309-4. Epub 2021 Jan 2. 18 Additional Amino Acids of the Signal Peptide of the Bombyx mori Nucleopolyhedrovirus GP64 Activates Immunoglobulin Binding Protein (BiP) Expression by RNA-seq Analysis RNA-seq分析家蚕核多角体病毒GP64信号肽的18个额外氨基酸激活免疫球蛋白结合蛋白（BiP）的表达
ACS Appl Mater Interfaces. 2021 Feb 10;13(5):6043-6052.doi: 10.1021/acsami.0c21223. Epub 2021 Feb 1.A CRISPR-Cas9-Based Near-Infrared Upconversion-Activated DNA Methylation Editing System基于CRISPR-Cas9的近红外上转换激活DNA甲基化编辑系统 (IF:8.3).
Pharmacol Res. 2021 Jan;163:105230.doi:10.1016/j.phrs.2020.105230. Epub 2020 Oct 5. Long noncoding RNA AK039312 and AK079370 inhibits bone formation via miR-199b-5p长非编码RNA AK039312和AK079370抑制骨形成
Cell Death Differ. 2021 Jan;28(1):337-348.doi: 10.1038/s41418-020-00620-y. Epub 2020 Sep 9. RPS23RG1 modulates tau phosphorylation and axon outgrowth through regulating p35 proteasomal degradation RPS23RG1通过调节p35蛋白酶体降解调节tau磷酸化和轴突生长
Pharmacol Res. 2020 Oct 5;105230. doi: 10.1016/j.phrs.2020.105230 Long noncoding RNA AK039312 and AK079370 inhibits bone formation via miR-199b-5p
Biochem Biophys Res Commun. 2020 Dec10;533(3):613-619.doi:10.1016/j.bbrc.2020.09.063. Epub 2020 Sep 25. Prefoldin subunit MM1 promotes cell migration via facilitating filopodia formation预折叠蛋白亚单位MM1通过促进细胞迁移
Graefes Arch Clin Exp Ophthalmol. 2020 Oct;258(10):2251-2261.doi: 10.1007/s00417-020-04636-5.Epub 2020 Jun 7.Disease-causing mutations associated with bestrophinopathies promote apoptosis in retinal pigment epithelium cells.视网膜色素上皮细胞凋亡
Biochem Pharmacol. 2020 Jul;177:113984.doi:10.1016/j.bcp.2020.113984. Epub 2020 Apr 18. Ethyl-p-methoxycinnamate enhances oct4 expression and reinforces pluripotency through the NF-κB signaling pathway对甲氧基肉桂酸乙酯增强oct4表达并增强多能性
Small.2020 Jul;16(30):e1907301.doi: 10.1002/smll.201907301. Epub 2020 Jun 25.Photoactivatable RNA N 6 -Methyladenosine Editing with CRISPR-Cas13甲基腺苷编辑(IF:13.281).
Small. 2020 Jul;16(30):e1907301.doi: 10.1002/smll.201907301. Epub 2020 Jun 25. Photoactivatable RNA N6 -Methyladenosine Editing with CRISPR-Cas13 CRISPR-Cas13编辑可光激活RNA N6-甲基腺苷 (IF:13.3).
Front Genet.2020 May 26;11:511.doi: 10.3389/fgene.2020.00511. eCollection 2020.MICA ∗ 012:01 Allele Facilitates the Metastasis of KRAS-Mutant Colorectal Cancer.KRAS突变型结直肠癌的转移
J Ethnopharmacol. 2020 Mar 25:250:112499.doi: 10.1016/j.jep.2019.112499. Epub 2019 Dec 23. Ethanol extract of Elephantopus scaber Linn. Attenuates inflammatory response via the inhibition of NF-κB signaling by dampening p65-DNA binding activity in lipopolysaccharide-activated macrophages 非洲象的乙醇提取物。通过抑制脂多糖激活的巨噬细胞中p65 DNA结合活性抑制NF-κB信号传导来减轻炎症反应 (IF:5.195).
J Cell Biochem. 2019 Sep;120(9):14326-14335.doi: 10.1002/jcb.28538. Epub 2019 May 20. Bom-miR-2805 upregulates the expression of Bombyx mori fibroin light chain gene in vivo. Bom-miR-2805上调体内家蚕丝素轻链基因的表达。
Genes Dis.2019 Sep 17;8(1):94-109.doi: 10.1016/j.gendis.2019.09.005. eCollection 2021 Jan.SFs mediate the function of AR in the ovarian granulosa cells of patients with PCOS.SRSFs介导多囊卵巢综合征患者卵巢颗粒细胞AR的功能
Genes Dis. 2019 Sep 17;8(1):94-109.doi: 10.1016/j.gendis.2019.09.005. eCollection 2021 Jan. SRSFs mediate the function of AR in the ovarian granulosa cells of patients with PCOS SRSFs介导多囊卵巢综合征患者卵巢颗粒细胞AR的功能 (IF:6.9).
J Cell Physiol . 2019 Jul;234(7):11524-11536. doi: 10.1002/jcp.27815. Epub 2019 Jan 17. A novel long noncoding RNA AK016739 inhibits osteoblast differentiation and bone formation
Eur Rev Med Pharmacol Sci.2019 Apr;23(8):3291-3301.doi: 10.26355/eurrev_201904_17691.Increased long noncoding RNA LINC00511 is correlated with poor prognosis and contributes to cell proliferation and metastasis by modulating miR-424 in hepatocellular carcinoma.长链非编码RNA LINC00511与肝细胞癌预后不良相关，并通过调节miR-424促进细胞增殖和转移
ACS Sens.2019 Apr 26;4(4):977-983.doi: 10.1021/acssensors.9b00102. Epub 2019 Mar 21.Rapidly Visualizing the Membrane Affinity of Gene Vectors Using Polydiacetylene-Based Allochroic Vesicles.(IF:7.711).
Gene.2019 Mar10;688:98-106. doi:10.1016/j.gene.2018.11.095.
Embryonic morphology observation and HOXC8 gene expression in crest cushions of Chinese Crested duck
J Cell Physiol . 2018 Jul;233(7):5405-5419. doi: 10.1002/jcp.26374. Epub 2018 Jan 23. Mechanical unloading reduces microtubule actin crosslinking factor 1 expression to inhibit β-catenin signaling and osteoblast proliferation
Oncol Lett . 2018 Apr;15(4):4344-4350. doi: 10.3892/ol.2018.7831. Epub 2018 Jan 19. Synergistic effect of receptor-interacting protein 140 and simvastatin on the inhibition of proliferation and survival of hepatocellular carcinoma cells
Toxicol Appl Pharmacol . 2017 May 1;322:75-88. doi: 10.1016/j.taap.2017.03.003. Epub 2017 Mar 8. Molecular mechanisms of 3,3’4,4′,5-pentachlorobiphenyl-induced epithelial-mesenchymal transition in human hepatocellular carcinoma cells
Mol Med Rep . 2016 Feb;13(2):1725-31. doi: 10.3892/mmr.2015.4704. Epub 2015 Dec 22. Myricetin inhibits Kv1.5 channels in HEK293 cells.
Nat Commun . 2015 Aug 24;6:8022. Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway. (IF:11.329).
Mol Cell Biol . 2015 Jul;35(14):2400-13. doi: 10.1128/MCB.00090-15. Epub 2015 May 4. SOCS3 Drives Proteasomal Degradation of TBK1 and Negatively Regulates Antiviral Innate Immunity
Oncotarget . 2015 May 30;6(15):13049-59. Wedelolactone disrupts the interaction of EZH2-EED complex and inhibits PRC2-dependent cancer. (IF:6.359).
Eur J Med Chem . 2014 Oct 6;85:119-26. doi: 10.1016/j.ejmech.2014.07.091. Epub 2014 Jul 25. Discovery of highly potent TNFα inhibitors using virtual screen.
Biochem Biophys Res Commun . 2014 Apr 4;446(2):523-8. doi: 10.1016/j.bbrc.2014.02.137. Epub 2014 Mar 12. eEF1Bγ is a positive regulator of NF-кB signaling pathway.
Int J Nanomedicine . 2013;8:3805-16. doi: 10.2147/IJN.S48950. Epub 2013 Oct 2. Efficacy and safety of dendrimer nanoparticles with coexpression of tumor necrosis factor-α and herpes simplex virus thymidine kinase in gene radiotherapy of the human uveal melanoma OCM-1 cell line. (IF:6.400).
J Immunol . 2013 Sep 1;191(5):2614-23. doi: 10.4049/jimmunol.1203143. Epub 2013 Aug 5. Enhancer of zeste homolog 2 is a negative regulator of mitochondria-mediated innate immune responses.
Appl Microbiol Biotechnol . 2013 Jul;97(14):6301-14. doi: 10.1007/s00253-013-4787-z. Epub 2013 Mar 6. Design, expression and characterization of a novel coexpression system of two antiarthritic molecules.
Heart Vessels . 2013 May;28(3):385-96. doi: 10.1007/s00380-012-0275-0. Epub 2012 Sep 1. Real-time tracking of adipose tissue-derived stem cells with injectable scaffolds in the infarcted heart.
PLoS One . 2012;7(11):e49567. doi:10.1371/journal.pone.0049567. Epub 2012 Nov 19. The ubiquitin ligase TRAF6 negatively regulates the JAK-STAT signaling pathway by binding to STAT3 and mediating its ubiquitination.
EntransterTM系列转染试剂的成分和原理，化学结构，粒径，电位等数据
siRNA转染与DNA转染有什么不一样?
为什么EntransterTM转染试剂有血清转染不仅没有毒性，反而有助于提高转染效率?
为什么EntransterTM系列转染试剂转染时可以有抗生素，而脂质体转染对抗生素敏感?
常温运输，于4℃长期存储，有效期12个月。
本品使用安全，未发现任何生物、化学毒性。如不慎沾染，用清水冲洗即可。
北京英格恩生物科技有限公司本产品实行严格质量检验，并进行转染验证，以确保产品质量。请用户使用前务必认真阅读操作手册。如用户仍然有问题，请立即联系本公司人员，英格恩公司将负责提供全程技术服务。
本品仅限科研用途。
